Mechanism of baicalein in treatment of castration-resistant prostate cancer based on network pharmacology and cell experiments

• Main Authors: Baokai Dou (Author), Yingjie Cui (Author), Qianqian Zhou (Author), Jiawei Fu (Author), Yi Zhou (Author), Xiwu Zhang (Author), Qi Zhang (Author), Jing Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ObjectiveBaicalein, one of the most abundant flavonoids found in Chinese herb Scutellaria baicalensis Georgi, exhibits pharmacological activities against various cancers. However, the precise pharmacological mechanism of baicalein in treating castration-resistant prostate cancer (CRPC) remains elusi...