OPCML is hypermethylated in a subset of patients with metaplastic changes in their esophagus

• Główni autorzy: Natalia Castaño-Rodríguez (Autor), Georgia L. Popple (Autor), Gloria Liliana Porras-Hurtado (Autor), José Luis Cardona-Deazza (Autor), Juan José Montoya-Martinez (Autor), Antonio Javier Cadavid-Velez (Autor), Héctor William Toro-Hidalgo (Autor), Alba Ruth Cobo-Alvarado (Autor), Ofelia del Socorro Hincapié-Rincón (Autor), Stephen M. Riordan (Autor), Nadeem O. Kaakoush (Autor)
• Format: Książka
• Wydane: BMC, 2018-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract OPCML hypermethylation is considered a promising cancer biomarker. We examined methylation levels in the first exon of OPCML in two patient cohorts within the esophageal adenocarcinoma and gastric adenocarcinoma cascades and in a range of cell-lines using a custom PyroMark CpG assay. Methyl...