FH535 Suppresses Osteosarcoma Growth In Vitro and Inhibits Wnt Signaling through Tankyrases

Osteosarcoma (OS) is an aggressive primary bone tumor which exhibits aberrantly activated Wnt signaling. The canonical Wnt signaling cascade has been shown to drive cancer progression and metastasis through the activation of β-catenin. Hence, small molecule inhibitors of Wnt targets are being explor...

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Bibliographic Details
Main Authors: Carl T. Gustafson (Author), Tewodros Mamo (Author), Kristen L. Shogren (Author), Avudaiappan Maran (Author), Michael J. Yaszemski (Author)
Format: Book
Published: Frontiers Media S.A., 2017-05-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available