Poorly neutralizing polyclonal antibody in vitro against coxsackievirus A16 circulating strains can prevent a lethal challenge in vivo

• المؤلفون الرئيسيون: Xin Yao (مؤلف), QunYing Mao (مؤلف), Yajing Li (مؤلف), Chunsheng Hao (مؤلف), LianLian Bian (مؤلف), Pan Chen (مؤلف), Fan Gao (مؤلف), Xing Wu (مؤلف), WeiWei Lu (مؤلف), Qiang Gao (مؤلف), XiuLing Li (مؤلف), Zhenglun Liang (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2018-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Neutralizing antibodies (NTAbs) is a major criterion for evaluation the immunogenicity of many vaccines, for example, poliovirus and EV71 vaccine. Here, we firstly discovered that polyclonal antibodies induced by inactivated CVA16 vaccine and lived CVA16 virus have poor ability to neutralize circula...