A Bidirectional Permeability Assay for beyond Rule of 5 Compounds

• Main Authors: Yunhai Cui (Author), Cyril Desevaux (Author), Ines Truebenbach (Author), Peter Sieger (Author), Klaus Klinder (Author), Alan Long (Author), Achim Sauer (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bidirectional permeability measurement with cellular models grown on Transwell inserts is widely used in pharmaceutical research since it not only provides information about the passive permeability of a drug, but also about transport proteins involved in the active transport of drug substances acro...