Host protein ABCE1 interacts with the viral phosphoprotein and promotes rabies virus replication

• Main Authors: Xing Liu (Author), Jiwen Zhang (Author), Fang Li (Author), Yibrah Tekle Hagoss (Author), Weldu Tesfagaber (Author), Lulu Wang (Author), Zilong Wang (Author), Dongming Zhao (Author), Zhigao Bu (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rabies virus (RABV) phosphoprotein (P) plays an important role in disrupting host interferon (IFN)-mediated antiviral immune response. ABCE1 is known as an RNase L inhibitor that negatively regulates the 2',5'-oligoadenylate (2-5A)/RNase L antiviral system related to the IFN signaling path...