Transplantation of hMSCs Genome Edited with LEF1 Improves Cardio-Protective Effects in Myocardial Infarction

• Main Authors: Hyun-Min Cho (Author), Kang-Hoon Lee (Author), Yi-ming Shen (Author), Tae-Jin Shin (Author), Pan-Dong Ryu (Author), Min-Cheol Choi (Author), Kyung-Sun Kang (Author), Je-Yoel Cho (Author)
• Format: Book
• Published: Elsevier, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stem cell-based therapy is one of the most attractive approaches to ischemic heart diseases, such as myocardial infarction (MI). We evaluated the cardio-protective effects of the human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) stably expressing lymphoid enhancer-binding factor...