Towards a better detection of patients at-risk of linezolid toxicity in clinical practice: a prospective study in three Belgian hospital centers

• Main Authors: Hélène Thirot (Author), David Fage (Author), Antonia Leonhardt (Author), Philippe Clevenbergh (Author), Tatiana Besse-Hammer (Author), Jean Cyr Yombi (Author), Olivier Cornu (Author), Caroline Briquet (Author), Maya Hites (Author), Frédérique Jacobs (Author), Gert-Jan Wijnant (Author), Sebastian G. Wicha (Author), Frédéric Cotton (Author), Paul M. Tulkens (Author), Anne Spinewine (Author), Françoise Van Bambeke (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Linezolid is a last-resort antibiotic for infections caused by multidrug-resistant microorganisms. It is widely used for off-label indications and for longer than recommended treatment durations, exposing patients at higher risk of adverse drug reactions (ADRs), notably thrombocytopeni...