Colchicine modulates TIMP1, MMP1, and pMAP4 expression to enhance extracellular matrix degradation in 3T3 fibroblast-mediated myocardial infarction

• Main Authors: Saskia Dyah Handari (Author), Mohammad Saifur Rahman (Author), Djanggan Sargowo (Author), Aulanni'am Aulanni'am (Author), Bayu Lestari (Author), Delvac Oceandy (Author)
• Format: Book
• Published: GarVal Editorial Ltda., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context: Cardiovascular disease is a leading cause of mortality worldwide. Following acute myocardial infarction (AMI), cardiac cells release many cytokines and proteolytic enzymes that regulate the extracellular matrix (ECM), including matrix metalloproteinases (MMPs), tissue inhibitor of metallopr...