Development of Liposome containing sodium deoxycholate to enhance oral bioavailability of itraconazole

• Main Authors: Zhenbao Li (Author), Meiyu Zhang (Author), Chang Liu (Author), Shiwei Zhou (Author), Wenjuan Zhang (Author), Tianyang Wang (Author), Mei Zhou (Author), Xiaohong Liu (Author), Yongjun Wang (Author), Yinghua Sun (Author), Jin Sun (Author)
• Format: Book
• Published: Elsevier, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to enhance oral bioavailability of itraconazole (ITZ) by developing Liposome containing sodium deoxycholate (ITZ-Lip-NaDC). The liposome, consisting of egg yolk lecithin and sodium deoxycholate, was prepared by thin-film dispersion method. Differential Scanning Calorimetry...