Monosomal karyotype as an adverse risk factor for inferior survivals in children with acute myeloid leukemia

• Main Authors: Xingjuan Wang (Author), Xi Chen (Author), Hu Dou (Author), Zhenzhen Yang (Author), Junqin Bi (Author), Yi Huang (Author), Guo Fu (Author), Lan Yuan (Author), Ling Lu (Author), Jie Yu (Author), Liming Bao (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Although monosomal karyotype (MK) has been recognized as an adverse risk factor in adult acute myeloid leukemia (AML), its impact on pediatric AML outcomes remains unclear. Methods: Clinical characteristics, cytogenetic and molecular profiling, and prognostic impact of MK were analyzed i...