Early myopathy in Duchenne muscular dystrophy is associated with elevated mitochondrial H2O2 emission during impaired oxidative phosphorylation

Early myopathy in Duchenne muscular dystrophy is associated with elevated mitochondrial H2O2 emission during impaired oxidative phosphorylation

Abstract Background Muscle wasting and weakness in Duchenne muscular dystrophy (DMD) causes severe locomotor limitations and early death due in part to respiratory muscle failure. Given that current clinical practice focuses on treating secondary complications in this genetic disease, there is a cle...

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Main Authors: Meghan C. Hughes (Author), Sofhia V. Ramos (Author), Patrick C. Turnbull (Author), Irena A. Rebalka (Author), Andrew Cao (Author), Cynthia M.F. Monaco (Author), Nina E. Varah (Author), Brittany A. Edgett (Author), Jason S. Huber (Author), Peyman Tadi (Author), Luca J. Delfinis (Author), U. Schlattner (Author), Jeremy A. Simpson (Author), Thomas J. Hawke (Author), Christopher G.R. Perry (Author)
Format: Book
Published: Wiley, 2019-06-01T00:00:00Z.
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3rd Floor Main Library

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