Linking Tumor Growth Dynamics to Survival in Ipilimumab‐Treated Patients With Advanced Melanoma Using Mixture Tumor Growth Dynamic Modeling

• Main Authors: Yan Feng (Author), Xiaoning Wang (Author), Satyendra Suryawanshi (Author), Akintunde Bello (Author), Amit Roy (Author)
• 格式: 图书
• 出版: Wiley, 2019-11-01T00:00:00Z.
• 主题: article
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Early tumor assessments have been widely used to predict overall survival (OS), with potential application to dose selection and early go/no‐go decisions. Most published tumor dynamic models assume a uniform pattern of tumor growth dynamics (TGDs). We developed a mixture TGD model to characterize di...