Alpha 2-adrenoceptor participates in anti-hyperalgesia by regulating metabolic demand

• Autores principales: Ke Zhang (Autor), Yu-Qing Ren (Autor), Yan Xue (Autor), Dongxia Duan (Autor), Tong Zhou (Autor), Ying-Zhuo Ding (Autor), Xiang Li (Autor), Wan-Kun Gong (Autor), Jiao-Qiong Guan (Autor), Le Ma (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The α2-adrenoceptor agonist dexmedetomidine is a commonly used drug for sedatives in clinics and has analgesic effects; however, its mechanism of analgesia in the spine remains unclear. In this study, we systematically used behavioural and transcriptomic sequencing, pharmacological intervention, ele...