Development and identification of a new Vero cell-based live attenuated influenza B vaccine by a modified classical reassortment method

• Main Authors: Fan Yang (Author), Lei Ma (Author), Jian Zhou (Author), Yinjie Wu (Author), Jingxia Gao (Author), Shaohui Song (Author), Xingliang Geng (Author), Qi Guo (Author), Zhuofan Li (Author), Weidong Li (Author), Guoyang Liao (Author), Yufeng Li (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: It was to generate a new Vero and cold-adapted live attenuated influenza B vaccine with enough safety and immunogenicity. Methods: According to modified classical reassortment method, the donor strain was B/Yunnan/2/2005Vca(B), and the parental virus strain was B/Brisbane/60/2008wt. Afte...