Initiation of prostate cancer in mice by Tp53R270H: evidence for an alternative molecular progression
SUMMARY Tp53 mutations are common in human prostate cancer (CaP), occurring with a frequency of ∼30% and ∼70% in localized and metastatic disease, respectively. In vitro studies have determined several common mutations of Tp53 that have specific gain-of-function properties in addition to loss of fun...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2012-11-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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