Dasatinib-Loaded Topical Nano-Emulgel for Rheumatoid Arthritis: Formulation Design and Optimization by QbD, In Vitro, Ex Vivo, and In Vivo Evaluation

• Hoofdauteurs: Mahipal Reddy Donthi (Auteur), Ranendra Narayan Saha (Auteur), Gautam Singhvi (Auteur), Sunil Kumar Dubey (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The current study aimed to develop a topical emulgel of dasatinib (DTB) for rheumatoid arthritis (RA) treatment to reduce systemic side effects. The quality by design (QbD) approach was employed to optimize DTB-loaded nano-emulgel using a central composite design (CCD). Emulgel was prepared using th...