Bioinformatics and functional analysis of an Entamoeba histolytica mannosyltransferase necessary for parasite complement resistance and hepatical infection.

• Main Authors: Christian Weber (Author), Samantha Blazquez (Author), Sabrina Marion (Author), Christophe Ausseur (Author), Divya Vats (Author), Mickael Krzeminski (Author), Marie-Christine Rigothier (Author), Rachid C Maroun (Author), Alok Bhattacharya (Author), Nancy Guillén (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The glycosylphosphatidylinositol (GPI) moiety is one of the ways by which many cell surface proteins, such as Gal/GalNAc lectin and proteophosphoglycans (PPGs) attach to the surface of Entamoeba histolytica, the agent of human amoebiasis. It is believed that these GPI-anchored molecules are involved...