Simulation‐based evaluation of personalized dosing approaches for anti‐FGFR/KLB bispecific antibody fazpilodemab

• Autores principales: Kenta Yoshida (Autor), Victor Poon (Autor), Ajit Dash (Autor), Rebecca Kunder (Autor), Leslie Chinn (Autor), Matts Kågedal (Autor)
• Formato: Libro
• Publicado: Wiley, 2024-04-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Personalized dosing approaches play important roles in clinical practices to improve benefit: risk profiles. Whereas this is also important for drug development, especially in the context of drugs with narrow therapeutic windows, such approaches have not been fully evaluated during clinical...