HMEJ-mediated site-specific integration of a myostatin inhibitor increases skeletal muscle mass in porcine
As a robust antagonist of myostatin (MSTN), follistatin (FST) is an important regulator of skeletal muscle development, and the delivery of FST to muscle tissue represents a potential therapeutic strategy for muscular dystrophies. The N terminus and FSI domain of FST are the functional domains for M...
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Elsevier,
2021-12-01T00:00:00Z.
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