Panax notoginseng saponins inhibits NLRP3 inflammasome-mediated pyroptosis by downregulating lncRNA-ANRIL in cardiorenal syndrome type 4

• Κύριοι συγγραφείς: Ying Xu (Συγγραφέας), Luxi Cao (Συγγραφέας), Wenli Zou (Συγγραφέας), Rizhen Yu (Συγγραφέας), Wei Shen (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2023-05-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Objective Cardiorenal syndrome type 4 (CRS4) is a complication of chronic kidney disease. Panax notoginseng saponins (PNS) have been confirmed to be efficient in cardiovascular diseases. Our study aimed to explore the therapeutic role and mechanism of PNS in CRS4. Methods CRS4 model rats an...