Structural simplification: an efficient strategy in lead optimization

The trend toward designing large hydrophobic molecules for lead optimization is often associated with poor drug-likeness and high attrition rates in drug discovery and development. Structural simplification is a powerful strategy for improving the efficiency and success rate of drug design by avoidi...

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Bibliographic Details
Main Authors: Shengzheng Wang (Author), Guoqiang Dong (Author), Chunquan Sheng (Author)
Format: Book
Published: Elsevier, 2019-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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