Rapid and Efficient Access to Novel Bio-Inspired 3-Dimensional Tricyclic SpiroLactams as Privileged Structures via Meyers' Lactamization

• Main Authors: Salia Tangara (Author), Léo Faïon (Author), Catherine Piveteau (Author), Frédéric Capet (Author), Romain Godelier (Author), Marion Michel (Author), Marion Flipo (Author), Benoit Deprez (Author), Nicolas Willand (Author), Baptiste Villemagne (Author)
• 格式: 图书
• 出版: MDPI AG, 2023-03-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

The concept of privileged structure has been used as a fruitful approach for the discovery of novel biologically active molecules. A privileged structure is defined as a semi-rigid scaffold able to display substituents in multiple spatial directions and capable of providing potent and selective liga...