Hemokinin-1 as a Mediator of Arthritis-Related Pain via Direct Activation of Primary Sensory Neurons

• Main Authors: Éva Borbély (Author), Ágnes Hunyady (Author), Krisztina Pohóczky (Author), Maja Payrits (Author), Bálint Botz (Author), Attila Mócsai (Author), Alexandra Berger (Author), Éva Szőke (Author), Zsuzsanna Helyes (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The tachykinin hemokinin-1 (HK-1) is involved in immune cell development and inflammation, but little is known about its function in pain. It acts through the NK1 tachykinin receptor, but several effects are mediated by a yet unidentified target. Therefore, we investigated the role and mechanism of...