Heterogeneous expression of EPCAM in human circulating tumour cells from patient-derived xenografts

• Main Authors: Chiara Agnoletto (Author), Linda Minotti (Author), Laura Brulle-Soumare (Author), Lorenzo Pasquali (Author), Marco Galasso (Author), Fabio Corrà (Author), Federica Baldassari (Author), Jean-Gabriel Judde (Author), Stefano Cairo (Author), Stefano Volinia (Author)
• Format: Book
• Published: BMC, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background We aim to characterize the heterogeneous circulating tumour cells (CTCs) in peripheral blood, independently of physical or immunological purification, by using patient-derived xenografts (PDXs) models. CTC studies from blood generally rely on enrichment or purification. Conversel...