Reduction of oxidative stress suppresses poly-GR-mediated toxicity in zebrafish embryos

The hexanucleotide (G4C2)-repeat expansion in the C9ORF72 gene is the most common pathogenic cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). This repeat expansion can be translated into dipeptide repeat proteins (DPRs), and distribution of the poly-GR DPR correlates w...

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Main Authors: Fréderike W. Riemslagh (Author), Rob F. M. Verhagen (Author), Esmay C. van der Toorn (Author), Daphne J. Smits (Author), Wim H. Quint (Author), Herma C. van der Linde (Author), Tjakko J. van Ham (Author), Rob Willemsen (Author)
Format: Book
Published: The Company of Biologists, 2021-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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