Crotamine/siRNA Nanocomplexes for Functional Downregulation of Syndecan-1 in Renal Proximal Tubular Epithelial Cells

Proteinuria drives progressive tubulointerstitial fibrosis in native and transplanted kidneys, mainly through the activation of proximal tubular epithelial cells (PTECs). During proteinuria, PTEC syndecan-1 functions as a docking platform for properdin-mediated alternative complement activation. Non...

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Bibliographic Details
Main Authors: Joana D'Arc Campeiro (Author), Wendy A. Dam (Author), Mirian A. F. Hayashi (Author), Jacob van den Born (Author)
Format: Book
Published: MDPI AG, 2023-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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