DLGAP1 directs megakaryocytic growth and differentiation in an MPL dependent manner in hematopoietic cells

Abstract Background The MPL protein is a major regulator of megakaryopoiesis and platelet formation as well as stem cell regulation. Aberrant MPL and downstream Jak/STAT signaling results in the development of the Myeloproliferative Neoplasms (MPN). The pathogenetic and phenotypic features of the cl...

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Main Authors: Boguslaw A. Kwiatkowski (Author), Nicolas R. Burwick (Author), Robert E. Richard (Author)
Format: Book
Published: BMC, 2019-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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