DLGAP1 directs megakaryocytic growth and differentiation in an MPL dependent manner in hematopoietic cells
Abstract Background The MPL protein is a major regulator of megakaryopoiesis and platelet formation as well as stem cell regulation. Aberrant MPL and downstream Jak/STAT signaling results in the development of the Myeloproliferative Neoplasms (MPN). The pathogenetic and phenotypic features of the cl...
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Format: | Book |
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BMC,
2019-07-01T00:00:00Z.
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A1234.567 |
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