A Purified Biflavonoid Extract From Selaginella moellendorffii Alleviates Gout Arthritis via NLRP3/ASC/Caspase-1 Axis Suppression

• Hoofdauteurs: Xueyan Zhang (Auteur), Yingbo Liu (Auteur), Guangrui Deng (Auteur), Bisheng Huang (Auteur), Guoyin Kai (Auteur), Keli chen (Auteur), Juan Li (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background: Activation of nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome plays a crucial role in gout. Selaginella moellendorffii has been confirmed effective for the treatment of gout in hospital preparations. Flavonoids, such as amentoflavone (AM), are the main acti...