Anti-rheumatic colchicine phytochemical exhibits potent antiviral activities against avian and seasonal Influenza A viruses (IAVs) via targeting different stages of IAV replication cycle

• Main Authors: Akram Hegazy (Author), Raya Soltane (Author), Ahlam Alasiri (Author), Islam Mostafa (Author), Ahmed M. Metwaly (Author), Ibrahim H. Eissa (Author), Sara H. Mahmoud (Author), Abdou Kamal Allayeh (Author), Noura M. Abo Shama (Author), Ahmed A. Khalil (Author), Ramya S. Barre (Author), Assem Mohamed El-Shazly (Author), Mohamed A. Ali (Author), Luis Martinez-Sobrido (Author), Ahmed Mostafa (Author)
• Format: Book
• Published: BMC, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The continuous evolution of drug-resistant influenza viruses highlights the necessity for repurposing naturally-derived and safe phytochemicals with anti-influenza activity as novel broad-spectrum anti-influenza medications. Methods In this study, nitrogenous alkaloids were teste...