Smooth muscle cell-targeted RNA ligand promotes accelerated reendothelialization in a swine peripheral injury model

• Main Authors: Beilei Lei (Author), Linda B. Liu (Author), Lauren Stokes (Author), Paloma H. Giangrande (Author), Francis J. Miller, Jr (Author), Saami K. Yazdani (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The local delivery of antiproliferative agents to inhibit neointimal growth is not specific to vascular smooth muscle cells (VSMC) and delays reendothelialization and vascular healing. This investigation was intended to evaluate the effect of luminal delivery of a VSMC-specific aptamer on endothelia...