In silico Study of New Five-Membered Heterocyclic Derivatives Bearing (1,3,4-oxadiazole and 1,3,4-thiadiazole) As Promising Cyclooxygenase Inhibitors

• Główni autorzy: Safa Adnan Mahmood (Autor), Monther F. mahdi (Autor), Ayad M R Rauf (Autor), Talal Aburjai (Autor)
• Format: Książka
• Wydane: College of Pharmacy / Mustansiriyah University, 2024-07-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

A novel series of pyrazole, oxadiazole and thiadiazole bearing Nabumetone moiety were designed, synthesized, and evaluated for their anti-inflammatory activity against cyclooxygenase enzyme 2, after Insilico assay (by molecular docking study) a best set has been synthesized and characterized. After...