Sodium-Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK-mTOR Signaling Pathway-Mediated Autophagy

• Main Authors: Changzhen Ren (Author), Kaiqiang Sun (Author), Yanda Zhang (Author), Yangxi Hu (Author), Bowen Hu (Author), Jian Zhao (Author), Zhiqing He (Author), Ru Ding (Author), Weizhong Wang (Author), Chun Liang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Sodium-glucose cotransporter-2 (SGLT2) inhibitors have been shown to decrease the adverse cardiac events and risks of cardiovascular mortality among patients with or without diabetes, which has made these drugs promising treatment options for patients with chronic heart failure. Cardiac...