Iron deficiency promotes aortic media degeneration by activating endoplasmic reticulum stress-mediated IRE1 signaling pathway

• Main Authors: Feng Shi (Author), Zhiwei Wang (Author), Qi Wu (Author), Xiaohan Zhong (Author), Min Zhang (Author), Bowen Li (Author), Wei Ren (Author), Shun Yuan (Author), Yuanyang Chen (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Aortic dissection (AD) is a macrovascular disease which is pathologically characterized by aortic media degeneration (AMD). Our team's previous research found that iron deficiency (ID) promoted the formation of AMD through presentative research. In this study, we aimed to investigat...