A multi-omics investigation of tacrolimus off-target effects on a proximal tubule cell-line

• मुख्य लेखकों: Hassan Aouad (लेखक), Quentin Faucher (लेखक), François-Ludovic Sauvage (लेखक), Emilie Pinault (लेखक), Claire-Cécile Barrot (लेखक), Hélène Arnion (लेखक), Marie Essig (लेखक), Pierre Marquet (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction: Tacrolimus, an immunosuppressive drug prescribed to a majority of organ transplant recipients is nephrotoxic, through still unclear mechanisms. This study on a lineage of proximal tubular cells using a multi-omics approach aims to detect off-target pathways modulated by tacrolimus that...