A multi-omics investigation of tacrolimus off-target effects on a proximal tubule cell-line

• Päätekijät: Hassan Aouad (Tekijä), Quentin Faucher (Tekijä), François-Ludovic Sauvage (Tekijä), Emilie Pinault (Tekijä), Claire-Cécile Barrot (Tekijä), Hélène Arnion (Tekijä), Marie Essig (Tekijä), Pierre Marquet (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2023-06-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Introduction: Tacrolimus, an immunosuppressive drug prescribed to a majority of organ transplant recipients is nephrotoxic, through still unclear mechanisms. This study on a lineage of proximal tubular cells using a multi-omics approach aims to detect off-target pathways modulated by tacrolimus that...