Gene targeting in amyotrophic lateral sclerosis using causality-based feature selection and machine learning

• Main Authors: Kyriaki Founta (Author), Dimitra Dafou (Author), Eirini Kanata (Author), Theodoros Sklaviadis (Author), Theodoros P. Zanos (Author), Anastasios Gounaris (Author), Konstantinos Xanthopoulos (Author)
• Format: Book
• Published: BMC, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Amyotrophic lateral sclerosis (ALS) is a rare progressive neurodegenerative disease that affects upper and lower motor neurons. As the molecular basis of the disease is still elusive, the development of high-throughput sequencing technologies, combined with data mining techniques...