Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism

• 主要な著者: Soufi Muhidien (著者), Lütjohann Dieter (著者), Krause Siegfried (著者), Büttner Petra (著者), Rennert Knut (著者), Mosig Sandy (著者), Heller Regine (著者), Funke Harald (著者)
• フォーマット: 図書
• 出版事項: BMC, 2008-11-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Elevated plasma cholesterol promotes the formation of atherosclerotic lesions in which monocyte-derived lipid-laden macrophages are frequently found. To analyze, if circulating monocytes already show increased lipid content and diffe...