Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism

• Main Authors: Soufi Muhidien (Author), Lütjohann Dieter (Author), Krause Siegfried (Author), Büttner Petra (Author), Rennert Knut (Author), Mosig Sandy (Author), Heller Regine (Author), Funke Harald (Author)
• Format: Book
• Published: BMC, 2008-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Elevated plasma cholesterol promotes the formation of atherosclerotic lesions in which monocyte-derived lipid-laden macrophages are frequently found. To analyze, if circulating monocytes already show increased lipid content and diffe...