Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism

• Autores principales: Soufi Muhidien (Autor), Lütjohann Dieter (Autor), Krause Siegfried (Autor), Büttner Petra (Autor), Rennert Knut (Autor), Mosig Sandy (Autor), Heller Regine (Autor), Funke Harald (Autor)
• Formato: Libro
• Publicado: BMC, 2008-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Elevated plasma cholesterol promotes the formation of atherosclerotic lesions in which monocyte-derived lipid-laden macrophages are frequently found. To analyze, if circulating monocytes already show increased lipid content and diffe...