A Proof-of-Concept Study on the Therapeutic Potential of Au Nanoparticles Radiolabeled with the Alpha-Emitter Actinium-225

• Main Authors: Evangelia-Alexandra Salvanou (Author), Dimitris Stellas (Author), Charalampos Tsoukalas (Author), Barbara Mavroidi (Author), Maria Paravatou-Petsotas (Author), Nikolaos Kalogeropoulos (Author), Stavros Xanthopoulos (Author), Franck Denat (Author), Gautier Laurent (Author), Rana Bazzi (Author), Stephane Roux (Author), Penelope Bouziotis (Author)
• Format: Book
• Published: MDPI AG, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Actinium-225 (²²⁵Ac) is receiving increased attention for its application in targeted radionuclide therapy, due to the short range of its emitted alpha particles in conjunction with their high linear energy transfer, which lead to the eradication of tumor cells while sparing n...