Novel mutations of the SRF gene in Chinese sporadic conotruncal heart defect patients

• Main Authors: Xu Mengmeng (Author), Xu Yuejuan (Author), Chen Sun (Author), Lu Yanan (Author), Li Fen (Author), Sun Kun (Author)
• Format: Knjiga
• Izdano: BMC, 2020-05-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Abstract Background Conotruncal heart defects (CTDs) are a group of congenital heart malformations that cause anomalies of cardiac outflow tracts. In the past few decades, many genes related to CTDs have been reported. Serum response factor (SRF) is a ubiquitous nuclear protein that acts as transcri...