Metabolite Profiling of Dihydroartemisinin in Blood of Plasmodium-Infected and Healthy Mice Using UPLC-Q-TOF-MSE

• المؤلفون الرئيسيون: Yifan Zhao (مؤلف), Peng Sun (مؤلف), Yue Ma (مؤلف), Xiaoqiang Chang (مؤلف), Xingyu Chen (مؤلف), Xin Ji (مؤلف), Yue Bai (مؤلف), Dong Zhang (مؤلف), Lan Yang (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Dihydroartemisinin (DHA) and its' derivatives have been employed as the most powerful first-line drugs for malarial treatment for several decades. The metabolism of DHA has not been studied clearly. Previous reports were focused on the pharmacokinetics procedure of DHA in healthy rats. The meta...