NiONP-Induced Oxidative Stress and Mitochondrial Impairment in an In Vitro Pulmonary Vascular Cell Model Mimicking Endothelial Dysfunction

• Main Authors: Ophélie Germande (Author), Thomas Ducret (Author), Jean-Francois Quignard (Author), Juliette Deweirdt (Author), Véronique Freund-Michel (Author), Marie-Hélène Errera (Author), Guillaume Cardouat (Author), Pierre Vacher (Author), Bernard Muller (Author), Patrick Berger (Author), Christelle Guibert (Author), Magalie Baudrimont (Author), Isabelle Baudrimont (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The development and use of nanomaterials, especially of nickel oxide nanoparticles (NiONPs), is expected to provide many benefits but also has raised concerns about the potential human health risks. Inhaled NPs are known to exert deleterious cardiovascular side effects, including pulmonary hypertens...