Functional G-Protein-Coupled Receptor (GPCR) Synthesis: The Pharmacological Analysis of Human Histamine H1 Receptor (HRH1) Synthesized by a Wheat Germ Cell-Free Protein Synthesis System Combined with Asolectin Glycerosomes

• Autori principali: Yasuyuki Suzuki (Autore), Tomio Ogasawara (Autore), Yuki Tanaka (Autore), Hiroyuki Takeda (Autore), Tatsuya Sawasaki (Autore), Masaki Mogi (Autore), Shuang Liu (Autore), Kazutaka Maeyama (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2018-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

G-protein-coupled receptors (GPCRs) are membrane proteins distributed on the cell surface, and they may be potential drug targets. However, synthesizing GPCRs in vitro can be challenging. Recently, some cell-free protein synthesis systems have been shown to produce a large amount of membrane protein...