Protective Role of trans-Chalcone against the Progression from Simple Steatosis to Non-alcoholic Steatohepatitis: Regulation of miR-122, 21, 34a, and 451

• Principais autores: Elham Karimi-Sales (Autor), Sajad Jeddi (Autor), Abbas Ebrahimi-Kalan (Autor), Mohammad Reza Alipour (Autor)
• Formato: Livro
• Publicado em: Tabriz University of Medical Sciences, 2022-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Purpose: Non-alcoholic steatohepatitis (NASH) is an inflammatory disorder and an aggressive form of fatty liver disease. Certain microRNAs, including miR-122, 21, 34a, and 451, are involved in the transition from steatosis to NASH. This study examined how trans-chalcone (the core of chalcone derivat...