Precise nano-system-based drug delivery and synergistic therapy against androgen receptor-positive triple-negative breast cancer

• Main Authors: Fangyan Gao (Author), Yueyao Wu (Author), Runtian Wang (Author), Yuhui Yao (Author), Yiqiu Liu (Author), Lingling Fan (Author), Jingtong Xu (Author), Jian Zhang (Author), Xin Han (Author), Xiaoxiang Guan (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Targeting androgen receptor (AR) has shown great therapeutic potential in triple-negative breast cancer (TNBC), yet its efficacy remains unsatisfactory. Here, we aimed to identify promising targeted agents that synergize with enzalutamide, a second-generation AR inhibitor, in TNBC. By using a strate...