Saturated Fatty Acid Emulsions Open the Blood-Brain Barrier and Promote Drug Delivery in Rat Brains

• Main Authors: Kyoung Su Sung (Author), Won Ho Cho (Author), Seung Heon Cha (Author), Yong-Woo Kim (Author), Seon Hee Choi (Author), Hak Jin Kim (Author), Mi Sook Yun (Author)
• Format: Book
• Published: MDPI AG, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We performed this study to evaluate whether saturated fatty acid (SFA) emulsions affect the BBB and determine the duration of BBB opening, thereby promoting drug delivery to the brain. Butyric, valeric, caproic, enanthic, and caprylic acid emulsions were infused into the carotid artery of the rat mo...