Pathological and immunological evaluation of different regimens of praziquantel treatment in a mouse model of Schistosoma mansoni infection.

• Main Authors: Ulrich Membe Femoe (Author), Hermine Boukeng Jatsa (Author), Valentin Greigert (Author), Julie Brunet (Author), Catherine Cannet (Author), Mérimé Christian Kenfack (Author), Nestor Gipwe Feussom (Author), Joseph Bertin Kadji Fassi (Author), Emilenne Tienga Nkondo (Author), Ahmed Abou-Bacar (Author), Alexander Wilhelm Pfaff (Author), Théophile Dimo (Author), Pierre Kamtchouing (Author), Louis-Albert Tchuem Tchuenté (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>One of the considerable challenges of schistosomiasis chemotherapy is the inefficacy of praziquantel (PZQ) at the initial phase of the infection. Immature schistosomes are not susceptible to PZQ at the curative dose. Here, we investigated the efficacy of different PZQ...