Identification and validation of diagnostic biomarkers for intrahepatic cholestasis of pregnancy based on untargeted and targeted metabolomics analyses of urine metabolite profiles

Abstract Background Intrahepatic cholestasis of pregnancy (ICP) is a prevalent pregnancy-specific complication that presents with maternal itching and elevated serum bile acid levels. ICP is associated with unfavorable pregnancy outcomes, severely decreasing the pregnant woman's quality of life...

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Main Authors: Weici Liu (Author), Lingyan Chen (Author), Keyan Miao (Author), Yilan You (Author), Jingyang Li (Author), Jianfeng Lu (Author), Yan Zhang (Author)
Format: Book
Published: BMC, 2023-11-01T00:00:00Z.
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