Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats

• Asıl Yazarlar: Yoo-Kyung Song (Yazar), Jin-Ha Yoon (Yazar), Jong Kyu Woo (Yazar), Ju-Hee Kang (Yazar), Kyeong-Ryoon Lee (Yazar), Seung Hyun Oh (Yazar), Suk-Jae Chung (Yazar), Han-Joo Maeng (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2020-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The potential inhibitory effect of quercetin, a major plant flavonol, on breast cancer resistance protein (BCRP) activity was investigated in this study. The presence of quercetin significantly increased the cellular accumulation and associated cytotoxicity of the BCRP substrate mitoxantrone in huma...